About this 3D model

This is a model of human Glutathione Transferase P1-1 (GSTP1-1). This model is somewhat special to me. It is one of the first structures I solved as a PhD student. Glutathione transferases (aka GSTs)are detoxifying enzymes that catalyze the conjugation of reduced glutathione (GSH), a tripeptide, to xenobiotic substrates, rendering them more soluble. The human pi-class GST, GSTP1-1, consists of two monomers (in green and red in the images). (The STL files contain surface representations of the two monomers "A" and "B".) A third STL file defines a glutathione molecule (in yellow in the images). Each monomer binds one glutathione molecule. Based on PDB entry 5GSS: http://www.rcsb.org/pdb/explore.do?structureId=5gss STL files created using VMD: http://www.ks.uiuc.edu/Research/vmd/